Additional cytotoxic diacetylenes from the stony coral Montipora sp.
نویسندگان
چکیده
Three new diacetylenes (1, 4, 6) have been isolated as cytotoxic constituents from the methanolic extract of the stony coral Montipora sp. The structures have been elucidated on the basis of spectroscopic evidence. The compounds were evaluated for cytotoxicity against a small panel of human tumor cell lines and showed moderate to significant activity.
منابع مشابه
Complete Genome Sequence of Pseudoalteromonas sp. Strain OCN003, Isolated from Kāne’ohe Bay, O’ahu, Hawaii
Pseudoalteromonas sp. strain OCN003 is a marine gammaproteobacterium that was isolated from a diseased colony of the common Hawaiian reef coral, Montipora capitata, found on a reef surrounding Moku o Lo'e in Kāne'ohe Bay, Hawaii. Here, we report the complete genome of Pseudoalteromonas sp. strain OCN003.
متن کاملTranscriptomic Resilience of a Coral Holobiont to Low pH
Ocean acidification is considered as one of the major threats for coral reefs at a global scale. Marine calcifying organisms, including stony corals, are expected to be the most affected by the predicted decrease of the surface water pH at the end of the century. The severity of the impacts on coral reefs remains as matter of controversy. Although previous studies have explored the physiologica...
متن کاملSynthesis and cytotoxic activity of a series of diacetylenic compounds related to falcarindiol.
The synthesis of a series of diacetylenic compounds related to the natural product falcarindiol has been carried out. Unsymmetrical diacetylenes were prepared by a modification of the Cadiot-Chodkiewicz coupling reaction, while a Glaser coupling was used to prepare symmetrical diacetylenes. These compounds have been tested for in vitro cytotoxic activity against Hep-G2, and H-4-II-E cell lines....
متن کاملVibrio owensii Induces the Tissue Loss Disease Montipora White Syndrome in the Hawaiian Reef Coral Montipora capitata
Incidences of coral disease in the Indo-Pacific are increasing at an alarming rate. In particular, Montipora white syndrome, a tissue-loss disease found on corals throughout the Hawaiian archipelago, has the potential to degrade Hawaii's reefs. To identify the etiologic agent of Montipora white syndrome, bacteria were isolated from a diseased fragment of Montipora capitata and used in a screen ...
متن کاملGenetic and morphological characterization of a coral Species of Concern, Montipora dilatata, in Kaneohe Bay, Oahu, Hawaii
Executive Summary Montipora dilatata (a stony coral endemic to Hawaii) is one of the rarest corals known; only a few colonies have ever been found despite extensive surveys. The taxonomic status of M. dilatata is unclear, in part because coral species boundaries in general are poorly understood. In order to examine evolutionary relationships in Montipora, a suite of molecular markers (mitochond...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 50 5 شماره
صفحات -
تاریخ انتشار 2002